Nur77: a potential therapeutic target in cancer

nuri77Nur77 (also known as TR3 and NGFI-B) is nuclear receptor subfamily 4 group A member 1 (NR4A1) 1, 2, 3, 4.In general, it acts as a transcription factor localized in the nucleusGeneration of MCK-Nur77 mice and animal husbandry. The murine Nur77 coding sequence was PCR amplified and cloned into the EcoRI site of the pCK4800 plasmid (gift of Eric Olson).The