HP Z840 and optimal PCIe slots utilization - Blackmagic

m2000 slotM2000-L8FC M2000 LTO8 FC 24-Slot 2U Tape Library M2000-L8FC LTO-8 With 24 slots and a capacity of up to 288 TB, The M2000 is the most economic massBut it's second PCIe slot only has x2 lanes. Should I expect a massive performance loss for the secondary GPU, or is it managable? I generally just use the 1050 as extra display ports, while